The Good Science Project

Venture Capital Has Lessons for Government and Philanthropy

tackling structural and bureaucratic rot

Feb 13 • Aishwarya Khanduja and Stuart Buck

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January 2026

Understanding and Modeling NIH Research Grant Success Rates and the Impact of “Multiyear Funding”

This is a guest post from Jeremy M.

Jan 30 • Stuart Buck

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Back and Forth on the Value of Replication

From Stuart:

Jan 29 • Stuart Buck and Jordan Dworkin

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Proposing an NIH High-Leverage Trials (HILT) Program: Large-scale Research for Repurposing and Supplements

An opportunity to lower medical costs and provide more effective treatments for all Americans by running high expected ROI trials that industry does not…

Jan 28 • Stuart Buck

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Update on Metascience-Related Language in the NIH Budget

Earlier this week, the House and Senate appropriations committees released a bipartisan bill on NIH funding, along with a Joint Explanatory Statement…

Jan 24 • Stuart Buck

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December 2025

The Economy of Knowing

Why Metascience Needs Micro and Macro

Dec 23, 2025 • Aishwarya Khanduja

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Recent Metascience News/Links

There are a number of news articles, scholarly articles, policy changes, and even a documentary film, that caught my eye recently:

Dec 18, 2025 • Stuart Buck

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Innovations in Scientific Institutions

Exciting times

Dec 13, 2025 • Stuart Buck

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A Good Science Manifesto

In late 2021, I started circulating a Good Science Manifesto for possible signatures (Tyler Cowen was the first).

Dec 11, 2025 • Stuart Buck

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November 2025

A Top Scientist's Ideas as to NIH

An anonymous guest post

Nov 22, 2025 • Stuart Buck

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October 2025

AI and Pediatric Cancer Research

The Trump Administration recently issued an executive order titled “Unlocking Cures for Pediatric Cancer with Artificial Intelligence,” with an…

Oct 29, 2025 • Stuart Buck

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A Compact Between Universities and Government?

Recently, the federal government released a proposed “Compact for Academic Excellence in Higher Education,” based on a proposal from investor Marc…

Oct 18, 2025 • Stuart Buck

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