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Regardless of who we choose, we will get the same outcome as we got under Francis S. Collins, M.D., Ph.D., rapidly falling life expectancy.

That's the bottom line, and it suggests that 90% of NIH money is wasted.

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Hard to know what to look like in an NIH director when it is not quite clear what the mission of the NIH is today. I was a bit surprised by the individuals you selected for the first list -- all distinguished research scientists and all old hands at academia and science policy unlikely to introduce novelty into NIH decision-making. I also thought you didn't quite give an accurate description of some of the individuals on the second list (who, I must note, are predominantly male). Goroff is a regular at NASEM and other DC-centric meetings and so no stranger to the world in which the NIH is imbedded. I found it odd that you did not mention that Geoff Ling is an MD/PhD. I do thank you for drawing attention to the career of the ever fascinating Warren Weaver for those who might not know of him. Sadly, the NIH Director must now be, primarily, a consummate politician charged with continually garnering a larger slice of the financial pie. You can't be both a defender of the status quo and the agent of change. And it does appear that we change -- as the budget of our national institute of health and the health of our nation seem inversely correlated.

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